
RETRA hydrobromide
CAS No. 1035875-01-4
RETRA hydrobromide( RETRA )
Catalog No. M10178 CAS No. 1035875-01-4
RETRA hydrobromide is a small molecule mutant p53 reactivator that activates a set of p53-regulated genes and specifically suppresses mutant p53-bearing tumor cells in vitro and in mouse xenograft.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
5MG | 873 | Get Quote |
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50MG | 1782 | Get Quote |
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100MG | 2250 | Get Quote |
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200MG | Get Quote | Get Quote |
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500MG | Get Quote | Get Quote |
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1G | Get Quote | Get Quote |
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Biological Information
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Product NameRETRA hydrobromide
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NoteResearch use only, not for human use.
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Brief DescriptionRETRA hydrobromide is a small molecule mutant p53 reactivator that activates a set of p53-regulated genes and specifically suppresses mutant p53-bearing tumor cells in vitro and in mouse xenograft.
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DescriptionRETRA hydrobromide is a small molecule mutant p53 reactivator that activates a set of p53-regulated genes and specifically suppresses mutant p53-bearing tumor cells in vitro and in mouse xenograft; increases in the expression level of p73, releases p73 and poduces tumor-suppressor effects similar to the functional reactivation of p53; a p73 activator.
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In Vitro——
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In Vivo——
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SynonymsRETRA
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PathwayApoptosis
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TargetMDM2-p53
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RecptorMDM2-p53
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Research Area——
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Indication——
Chemical Information
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CAS Number1035875-01-4
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Formula Weight350.245
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Molecular FormulaC11N11NO3S2.HBr
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Purity>98% (HPLC)
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Solubility——
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SMILESOC1=CC=C(C(CSC2=NCCS2)=O)C=C1O.[H]Br
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Chemical Name2-(4,5-dihydro-1,3-thiazol-2-ylthio)-1-(3,4-dihydroxyphenyl)ethanone hydrobromide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kravchenko JE, et al. Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6302-7.
2. Sonnemann J, et al. Eur J Cancer. 2015 May;51(7):841-51.
3. Santag S, et al. Oncogene. 2013 Aug 8;32(32):3676-85.
molnova catalog



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